His mother! Marc Andreessen, founder of A16z, a top venture capital firm in Silicon Valley, has directly provided a hardcore career breakthrough formula for the next 20 years. He clearly pointed out that if you are 22 years old, don't rush to blindly start a business. Immediately go to Silicon Valley to find the fastest-growing and most culturally hardcore companies to root in. Work hard for three years to accumulate an absolute advantage in the field of background research and reputation, while crazily screening the network of contacts that can work together to achieve success in the future. If you are 18 years old and just entered university, choose computer science with your eyes closed. He directly defined three absolute main tracks that can reshape the world: cryptocurrency and distributed systems, artificial intelligence and deep learning, and synthetic biology. Die hard on one of them. This is not only a development suggestion for young people, but also a future wealth blueprint that top capital is crazily betting on.