[U.S. Stock Market's Three Major Indexes Close Lower, Coinbase Drops Over 7%] The three major U.S. stock indexes collectively closed lower, with the Nasdaq down 2.15% and a cumulative weekly decline of 3.23%; the S&P 500 index fell 1.67%, with a cumulative weekly decline of 2.12%, marking its fifth consecutive weekly drop—the longest losing streak since 2022; the Dow Jones Industrial Average dropped 1.72%, with a cumulative weekly decline of 0.9%. Blockchain-related stocks broadly fell, including COIN (Coinbase) down 7.06%; MSTR (MicroStrategy) down 5.19%; CRCL (Circle) down 4.69%.