a16z|Dec 01, 2025 19:06
How OpenAI Builds for 800 Million Weekly Active Users: Model Specialization and Fine-Tuning
We sat down with Sherwin Wu, Head of Engineering at OpenAI Platform, to discuss OpenAI’s developer strategy, how to manage top ML teams, why they decided to start releasing open-weight models again, how prompt engineering has evolved over time, and how developer tools will shift to accommodate better agents moving forward.
00:00 Introduction
8:36 Horizontal vs vertical OpenAI
12:18 Why you can’t “disintermediate” the model
15:11 People build relationships with models
17:30 Not one AGI model but many
20:10 Fine-tuning, RFT, and customer data choices
24:44 Prompt engineering isn’t the point anymore
28:06 What an “agent” really is
31:55 How OpenAI thinks about pricing
36:46 Why open-weights don’t kill the API
42:57 Different stacks for text, images, video
45:47 How the agent builder actually works
@sherwinwu @martin_casado(a16z)
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