Priscilla Chan and Mark Zuckerberg on Curing All Disease We sat down with Dr. Priscilla Chan and Mark Zuckerberg, co-founders of the Chan Zuckerberg Initiative, to discuss their ambitious plan to cure, prevent, and manage all disease by the end of the century. CZI’s Biohub aims to generate vast biological datasets to train new frontier AI models to guide scientists in the lab, creating a feedback loop to accelerate the pace of basic science and take us towards a world without disease. 00:00 Introduction 03:42 Building tools to accelerate scientific discovery 07:03 Biohub = Frontier Biology + Frontier AI 13:32 "Most diseases should be thought of as rare diseases” 15:39 Inspiration: building a periodic table for biology 19:27 Why virtual cells? 21:17 The Biohub master plan 33:36 The importance of interface design in democratizing scientific discovery 35:34 How Biohub encourages cross-functional collaboration 40:38 Looking ahead: the broader impact of AI on biotech @bhorowitz @vintweeta @eriktorenberg(a16z)